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ARGiP Technologies - PROTEOLITIC AND BIO PRODUCTS

PEPSIN

1:10.000 > conf 10 Kg ---> Cod. P10KRG01
1:10.000 > conf 01 Kg ---> Cod. P01KRG01
1:10.000 > conf 10 g ---> Cod. PG10RG01

TECHNICAL DATASHEET:
Pepsin: 1:10.000 NF
Chemical Name: Peptidyl peptide hydrolase
Cas Number: 9001-75-6

RAW MATERIAL ANALYSIS:
Identification: Complies (NIR or Hemoglobine - digestive characteristic)
Appearance: Amorphous or crystalline, hygroscopic powder
Colour: from white to pale yellow
Density: 0,6 – 0,7 kg/l
Solubility: Very slightly soluble in water; insoluble in organic solvents
Appearance of Solution: Slightly opalescent with a weak acid reaction pH: 3,0 – 5,0 (1%)
Activity: > 10.000 NF
Yeasts And Moulds: < 10e2 cfu/g (TYMC, Ph. Eur. Current ed.) Pathogens: E. coli: negative/g (Ph. Eur. Current ed.) S. aureus: negative/10g (Ph. Eur. Current ed.)

GENERAL NOTICES:
Origin Of Raw Material: UK
Origin: porcine gastric mucosa
Description: Proteolytic enzyme content in gastric juice
Preservatives: None
Antioxidants: None
Allergens: free from food allergens (Reg. 1169/2011 EU, Annex II)
Latex free
Storage: Store in well closed containers, in refrigerator (+2/+8°C)
Store away from light and moisture

NOTES:
GMOs-free (Reg. 1829-1830/2003/EC)
BSE/TSE-free (complies with the EMEA guideline 410/01 rev. 03)
Melamine-free; dioxin-free

CLP:
H315 Causes skin irritation.
H317 May cause an allergic skin reaction.
H319 Causes serious eye irritation.
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled.
H335 May cause respiratory irritation.
P280 Wear protective gloves/protective clothing/eye protection face protection.
P302+P352 IF ON SKIN: Wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes.
Remove contact lenses, if present and easy to do. Continue rinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P337+P313 If eye irritation persists: Get medical advice/attention.


OMENTUM LIPIDS

Standard, conf 10 Kg ---> Cod. O10KRG01
Customized, conf 10 Kg  ---> Cod. O10KRG02

OMENTAL LIPIDS OVERVIEW:
The omentum is known to exhibit multiple therapeutic characteristics, and scientists continue to discover its remarkable benefits. Omental lipids come from the omentum, the tissue that helps protect the internal organs. It is able to limit the spread of infection while contributing to wound repair.

Studies have shown that omental lipids offer a number of unique characteristics:
Protective benefits result from mobility and structure
Defend against infections
Adhere to infected areas
Serve as effective surgical grafting medium
Angiogenic factors stimulate growth of new blood vessels
Rich in lipids, neutral glycerides, phospholipids, glycolipids, and gangliocides
Contain polypeptide growth factors (vascular endothelial growth factor) with angiogenic activity

Products containing omental lipids were used to minimize the occurrence of decubitus ulcers. It was concluded that the early use of products containing omental lipids, in at-risk subjects, can minimize decubitus ulcer formation. Bertoli et al (1999) conducted a study of 210 patients confined to bed: 22 presented decubitus ulcers, 45 local dystrophy, and 143 apparently unaffected skin where the medication was applied for pressure ulcer prevention. Period of application lasted 2-6 weeks (average 3.5 weeks). After treatment, 144 patients presented unaffected skin, two patients with ulcers went into remission, and 63 patients showed marked improvement in ulcers and local dystrophy (erythema, edema, de-epithelialization, maceration, and pain). The overall improvement was statistically significant (p<0.01).

Effectiveness and tolerability in patients suffering from chronic venous insufficiency:
Lisi et al (1993) studied 20 patients suffering from chronic venous insufficiency of the lower limbs. Evaluation of clinical effectiveness: excellent (disappearance of erythematic areas) 25%; good (considerable preventative action) 60%; satisfactory (slight preventative action) 15%.

FASTER HEALING:
In a study of 15 patients (data on file, 1990), each underwent four biopsies with 4mm diameter punches, two on the right parasacral area and two on the left parasacral area. One of the wounds made by the biopsies on each side was treated with a cream containing heterologous purified omental lipids (25%), while the other wound on each side was used as control. The cream was applied once daily for 28 days even after the wounds had healed. Measurements were made of the wounds’ external and internal diameters (with a micrometer and planimeter, respectively) and of their depth (with an ultrasound technique). The results showed that the wounds treated with the cream healed more quickly: 21.2 days as opposed to 25.1 days for the control wounds (p=0.001).

Significant improvement in skin conditions and increase in microcirculation in diabetic patients with polyneuropathic ulcers and skin dystrophy:
Rinaldi et al (1993) studied 25 patients suffering from polyneuropathic ulcers and widespread skin dystrophy caused by diabetes. On one of the legs, the skin areas surrounding the necrotic tissues were treated with P.O.L. CREAM; on the other, used as a control, a product containing Hyaluronic Acid was applied. Application of both topical products was made twice daily for 30 days. At the end of the follow-up period, the measurements of TEWL (transepidermal water loss), corneometry, sebometry, and pH values all showed significant improvement on the limbs treated with omentum, while the control limbs underwent varying evolution with some slight improvements but also a few cases of worsened conditions. Monitoring of microcirculation with the laser-doppler velocimeter showed no changes in limbs where only Hyaluronic Acid had been applied, but 13 of the limbs treated with the diabetic skin cream containing omentum derivative experienced significant improvement with an increase of 20% with respect to baseline values.

Favorable results in burn patients with chronic itching:
A Burn Impression Study (2005) followed 53 patients recovering from deep partial -and full- thickness burns with skin damaged to the point of destruction of sweat glands, leaving skin prone to chronic itching and dryness. 43 (81%) reported favorable results, six (11%) reported results equal to other interventions, while four (8%) reported unfavorable results.

Increase in oxidized hemoglobin in dystrophic skin:
Derming Institute (2003) studied 13 subjects. P.O.L. was applied twice daily to the inside of one forearm; the other arm was left untreated as a control. The quantity of oxidized hemoglobin in the skin was measured using a spectrophotometer: there was a statistically significant growth (p<0.001) in treated arm after 2 and 4 weeks treatment, while no significant difference was observed in the untreated arms.

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ARGiP Technologies - MECHANICAL TOOLS

CoHoRS Cod. 83013
COllection HOmogenization and Recording System

The new COHORS® system is a universal, fully automated homogenizing and grinding system for homogenization and extraction in one step. Unique designed vessels for disposable use complete the safe operation to avoid or even exclude cross-contamination and contacts with hazardous materia.

TECHNICAL FEATURES:

Size: 940x400x480 mm
Weight: Kg 50
Power supply: 110/220 Vac ± 10% 60/50Hz
Automatic operation: up to 12 samples
Temperature control: from 0° to 40°C
Running time: customizable running time
Running speed: from 1000 rpm up to 5000 rpm

AVAILABLE COLORS:

Orange (RAL 2008)
Black
Blue (RAL 5075)
Grey (RAL 7024)


Download COHORS instructions manual: english flag english flag english flag english flag english flag


MiniMAHFIA Cod. 83011
Semi-Automated Homogeniser for laboratory use

MiniMAHFIA is designed to achieve the best results in complete homogenisation of wide gam of samples. It can be used in laboratory for microbiology and chemical analysis sample preparation. Its use is suggested to all labs having a throughput of up to 30 samples to run per day.

TECHNICAL FEATURES:

Size: 260x370x495 mm
Weight: Kg 15
Power supply: 80 - 250 V
Absorb: 350 W

OPTIONAL TOOLS:

Additional racks (for FOODcons, FOODcons-MGM and FOODcons-Max)
FOODcons tray (it can hold up to 20 disposables)

FOODcons
Single use homogenizer for samples up to 80 ml

cod. 83300 FOODcons (plastic grinder 40ml)
cod. 83300 MGM FOODcons MGM (metal grinder 40ml)
cod. 83400 MAX FOODcons MAX (plastic grinder 80ml)
cod. 83400 MMX FOODcons MGMAX (metal grinder 80ml)

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